Masumeh Mohammadi

PhD in molecular medicine

Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Postal Code:1985717413

Telephone: 09124193927 / e-mail: mgm8362@gmail.com and m_gorgian@yahoo.com https://isid.research.ac.ir/Masoumeh_Mohammadi

Education:
I. Qualifications:
2013 PhD in molecular medicine, Tabriz Medical University
2009 M.Sc in medical virology, Tarbiat Modares University
2006 B.Sc in laboratory medicine, Esfahan Medical University

II. Thesis:
PhD thesis’ titles:
Effect of Visfatin and Resistin on Telomerase Gene Expression in Gastric Cancer AGS Cell Line.
M.S thesis’ titles:
Influence of light expression plasmid in kinetic of primary and memory CTL responses induced by HSV-1 DNA vaccine.

Projects:
I-   Finished:
1-   Resistin effects as a biomarker on bladder cancer.
2-   Effect of Visfatin and Resistin on Telomerase Gene Expression in Colorectal Cancer HCT116 Cell Line.
3-   Evalution of humolar and cellular immune responcse against HSV1 using genetic immunization by filamentous phage particles.
4-   Impact of timing strategy of LIGHT, a new TNF superfamily on immune platform induced by HSV-1 gB DNA vaccine.
5-   Calculating aggregation and heritability of the thyroid peroxidase autoantibody levels in the Tehran Lipid and Glucose Study (TLGS) population.
6-   Systematic review and meta-analysis of prognostic effect of visfatin in cancers.
7-   Systematic review and meta-analysis of circulating visfatin levels and cancer risk.
8-   The role of obesity in the tumorigenesis of gastric cancer.
9-   Adipocytokines in thyroid carcinomas.
10-   Epigenetic alteration in Medullary Thyroid Cancer.
11-   Circulating visfatin levels and cancers risk.
12-   Epigenetic alterations in endometrial cancer.

II-   Under process:
1-   Examination and comparison of thyroid tissue metabolome in different stages of papilary thyroid cancer with benign tumor and normal tissue.
2-   Chemerin serum levels in thyroid cancers.
3-   NVESTIGATION AND COMPARATION OF NKX2-1, PAX8 AND FOXE1 GENE EXPRESSION IN PAPILLARY THYROID CANCER TISSUE.

Publications:
I- Published Full text papers:
1- Masoumeh Mohammadi, Faezeh Mianabadi,Hassan Mehrad‐Majd. Circulating visfatin levels and cancers risk: A systematic review and meta‐analysis. C J Physiol. 2019; 234: 5011-5022.

2- Masoumeh Mohammadi, Jalil Hosseini, Morteza Fallah Karkan, Mehdi Hedayati. Serum Resistin levels in bladder cancer. Men’s Health Journal. 2018; 2 (1); e5.

3- Mohammadi M, Zarghami N, Hedayati M, Ghaemmaghami S. Synergistic effects of Resistin and Visfatin as adipocyte derived hormones on telomerase gene expression, in AGS gastric cancer cell line. Acta Medica Iranica. 2017 Oct;55(10):621-627.

4- Mohammadi M, Hedayati M. A Brief Review on The Molecular Basis of Medullary Tyroid Carcinoma. Cell journal. Volume 18, Number 4, Winter 2017, Serial Number: 72 Pages: 485-492.

5- Mohammadi M, Azizi F, Hedayati M. Iodine deficiency status in the WHO Eastern Mediterranean Region: a systematic review. Environ Geochem Health. 2017 Feb 21.

6- Mohammadi M. Oxidative stress and polycystic ovary syndrome: A brief review. International Journal of Preventive Medicine. (accepted)in press.

7- Mohammadi, M.; Hedayati, M.; Zarghami, N.; Ghaemmaghami, S. Resistin Effect on Telomerase Gene expression in Gastric Cancer Cell Line AGS. Acta Endo (Buc) 2016, 12 (2): 145-149.

8- Mohammadi, M.; Hedayati, M.; Zarghami, N.; Ghaemmaghami, S. Resistin Effect on HCT-116 Colorectal Cancer Cells Proliferation and Telomerase Expression. Acta Endocrinologica (1841-0987). Apr-Jun2016, Vol. 12 Issue 2, p145-149. 5p.

9- Gorgian Mohammadi M, Hedayati M, Zarghami N, Ghaemmaghami S, Mohaddes M. Adipocyte Derived Hormones Gene Expression, Resistin and visfatin, in AGS Gastric Cancer Cell line. (Iranian journal of cancer prevention, 2013, 6(3):165-9).

10- Gorgian Mohammadi M, Zarghami N , Hedayati M, Ghaemmaghami S , Rahmati-Yamchi M, Mohaddes M. Visfatin Effects on Telomerase Gene Expression in AGS Gastric Cancer Cell line. Indian J Cancer. 2015 Jan-Mar;52(1):32-5. doi: 10.4103/0019-509X.175567.

11- Gorgian Mohammadi M, Bamdad T, Parsania M, Hashemi HR, Puyanfard S. Kinetics of primary and memory cytotoxic T Lymphocytes Responses to Herpes Simplex Virus 1 Infection: Granzyme B Mediated CTL Activity. (Iranian Journal of Immunology. Volume 6, No. 1, March 2009).

12- Gorgian Mohammady M, Bamdad T, Parsania M, Soleimanjahi H, Pouyanfard S, Hashemi H, Asghari-Jafarabadi M. Effect of LIGHT adjuvant on kinetics of T-Cell Responses Induced by HSV-1 DNA Immunization. (Iranian Journal of Immunology. 2011 Jun; 8(2):76-84.)

13- Hashemi H, Bamdad T, Jamali A, Pouyanfard S, Gorgian Mohammadi M. Evalution of humolar and cellular immune responcse against HSV1 using genetic immunization by filamentous phage particles: a coparative approach to conventional DNA vaccine. (Journal of Virological Methods. Volume 163, Issue 2, February 2010, Pages 440-444).

14- Pouyanfard S, Bamdad T, Parsania M, Hashemi H, Gorgian Mohammadi M. Impact of timing strategy of LIGHT, a new TNF superfamily on immune platform induced by HSV-1 gB DNA vaccine. (Cytokine. 2010 Apr; 50(1):99-103. Epub 2010 Jan 22).

15- Sara Ghaemmaghami, Seyed Mojtaba Mohaddes, Mehdi Hedayati, Masumeh Gorgian Mohammadi, Golnoosh Dehbashi. Resistin and Visfatin Expression in HCT-116 Colorectal Cancer Cell Line. IJMCM, 2013, Vol 2, No 7.

16- Sara Ghaemmaghami, Mehdi Hedayati, Seyed Mojtaba Mohaddes, Masumeh Gorgian Mohammadi, Mohammad Rahmati, Nosratollah Zarghami. Visfatin Proliferative Effect on Hct-116 Colorectal Cancer Cell Line. Advances in Environmental Biology, 8(9) Special 2014, Pages: 55-60.

17- Sara Ghaemmaghami, Mehdi Hedayati, Seyed Mojtaba Mohaddes, Masumeh Gorgian Mohammadi, Amin Barkhordari. Resistin Effect on HCT-116 Colorectal Cancer Cells Proliferation and Telomerase Expression. Scimetr. 2014 April; 2(2): e16718.

18- Sepideh Mohammadi; Arash Mahboubi; Masumeh Mohammadi; Mehdi Hedayati, Arsalan Jalili. Assessing the Anticancer Effect of the Euphorbia condylocarpa Plant on AGS Gastric Cancer Cell Line. 2017. Gene, Cell and Tissue. 4(1): e41223 , DOI: 10.17795/gct-41223.

II-   Fulltext papers (under submittal process in international journals):
1-   Circulating visfatin levels and cancers risk: A systematic review and meta-analysis
2-   Epigenetic alterations in endometrial cancer: A brief review. First author
3-   The role of obesity in tumorigenesis and gastric cancer progression. (Review) First author
4-   Adipocytokines in thyroid carcinomas: a brief review First author
5-   A brief review on the epigenetic alteration in Medullary Thyroid Cancer First author
6-   Immune system in thyroid cancers. (Review) First author

Book publications:
I- Published books:
Ethics in genetic research, Persian language.
Genetics of cancer, Persian language.
Gene therapy, Persian language.
II- Uunder publication process books:
Immunology network in cancer

Abstract presentations and submissions:
1- Masumeh Gorgian mohammadi، M Hedayati، N Zarghami، S Ghaemmaghami، A Barkhordari. Does telomerase gene expression affect by Resistin in gastric cancer cell line AGS? (3th medical genetic congress in Tehran. 2013)

2- Gorgian Mohammadi M, Hedayati M, Zarghami N, Ghaemmaghami S, Mohaddes M. Adipocyte Derived Hormones Gene Expression, Resistin and visfatin, in AGS Gastric Cancer Cell line. (13th clinical biochemistry congress in Yazd. 2013)

3- Gorgian Mohammadi M, Zarghami N , Hedayati M, Ghaemmaghami S , A Rahmati. Visfatin Effects on Telomerase Gene Expression in AGS Gastric Cancer Cell line. (3th medical genetic congress in Tehran. 2013)

4- Gorgian Mohammady M, Bamdad T, Parsania M, Soleimanjahi H, Pouyanfard S, Hashemi H. Kinetic of cytotoxic T lymphocytes response to gB DNA vaccine comparing to Herpes Simplex Virus 1 infection. (5 th virology congress Tehran 2008)

5- Gorgian Mohammady M, Bamdad T, Parsania M, Soleimanjahi H, Pouyanfard S, Hashemi H. Evaluation of CTL responses against HSV-1 virus using Granzyme B ELISA in BALB/c mice. (second clinical microbiology congress in shiraz-1387)

6- Gorgian Mohammady M, Zarghami N, Hedayati M, Ghaemmaghami S, Mohaddes M. Synergic effects of Resistin and visfatin as adipocyte derived hormones on telomerase gene expression, in AGS gastric cancer cell line. (1th Iranian national congress of molecular medicine-Mashhad. 2013)

7- Mohammadi M, Hedayati M. A summary review of obesity and adipokines in gastric cancer. The Second International Gastrointestinal Cancer Congress will be held on 14 - 16 October 2015 in Tehran, Olympic Hotel.

8- Masoumeh Mohammadi. Oxidative stress in polycystic ovary syndrome. The Second national conference on molecular medicine, 18 February 2016, Tehran.

9- K. Guity1, M. Mohammadi1, A. Amoozegar1, M. Akbarzadeh1, F. Azizi2, M. Daneshpour Heritability of the thyroid peroxidase autoantibody levels in the Tehran Lipid and Glucose Study (TLGS(.European Conference of Human Genetics 2018. Milan, Italy.

10- Masoumeh Mohammadi, Mehdi Hedayati. A BRIEF REVIEW ON THE EPIGENETIC ALTERATION IN MEDULLARY THYROID CANCER. 12th International congress of endocrine disorder. 14-16 Nov 2018. Tehran.

Skills and Personal Qualities:
Laboratory techniques like cloning, immunostaining and flow cytometry, PCR, RT-PCR, Real
Time PCR, Real time PCR, cell culture and etc.
Communication skills, team work, problem solving (Powerpoint, Excel, SPSS, word,…).

Research interests:
Immune therapy, Gene and cell therapy, diagnosis research