Relationship between Lipid Accumulation Product and Visceral Adiposity Index with the Incidence of Chronic Kidney Disease
Relationship between Lipid Accumulation Product and Visceral Adiposity Index with the Incidence of Chronic Kidney Disease
Tehran Lipid and Glucose Study
Pouria Mousapour
Maryam Barzin (MD, Phd)
Farhad Hosseinpanah (MD)
Fereidoun Azizi (MD)
Obesity Research Center
Research Institute for Endocrine sciences
Shahid Beheshti University of Medical Sciences, Tehran, Iran
Obesity is associated with cardiovascular disorders, diabetes, liver and kidney diseases, and all-cause mortality.
Obesity is an independent factor for increasing the risk of CKD.
Organization WH. Obesity: preventing and managing the global epidemic: World Health Organization; 2000
Wahba IM et al. Clinical Journal of the American Society of Nephrology. 2007;2(3):550-62.
- Adiposity indices associated with incident CKD
Body mass index (BMI)
Waist circumference (WC)
Waist-to-hip ratio (WHR)
Waist-to-height ratio (WHtR)
Wang Y et al. Kidney international. 2008;73(1):19-33.
Elsayed EF et al. American Journal of Kidney Diseases. 2008;52(1):29-38.
Odagiri K et al. PloS one. 2014;9(2):e88873.
Noori N et al. Journal of Renal Nutrition. 2009;19(3):228-37.
- Lipid Accumulation Product (LAP) based on WC and triglycerides
- Visceral Adiposity Index (VAI) based on WC, BMI, triglycerides and HDL
- Acceptable prediction of metabolic disorders, cardiovascular events and mortality
Ioachimescu AG et al. Obesity. 2010;18(9):1836-44.
Bozorgmanesh M et al. Lipids in health and disease. 2010;9(1):45.
Chen H-Y et al. Cardiovascular diabetology. 2014;13(1):136.
- Association of LAP and VAI with existing renal dysfunction has been demonstrate in Former cross-sectional studies.
Huang J et al. International urology and nephrology. 2015;47(8):1387-96.
Xu X, Zhao Y et al. Therapeutics and clinical risk management. 2016;12:489.
Dai D, Chang Y et al. International journal of environmental research and public health. 2016;13(12):1231.
