The general characteristics of TIO patients
The gender distribution was even (M:F 19:20) with an average age of 42 (20–69 years).
Their course of disease was 6.7 ± 5.3 years (1.5–28 years).
Their symptoms included muscle weakness/fatigue (100%), bone pain (100%), trouble walking(100%), reduced height (64.1%), and pathological fractures (84.6%), primarily in the ribs, vertebral bodies, and femoral neck.