Hyperthyroidism and Pregnancy

Hyperthyroidism and Pregnancy

To review:

• Changes in thyroid economy during pregnancy
• Thyroid function tests in pregnancy
• Hyperthyroidism and pregnancy
• During pregnancy
•         Basal                                                                                                150
•         40-50 % increased T4 requirements                                  50-100
•          transfer of T4 and I from mother to fetus                           50
•          Increased renal clearance of I                                               ?
•                                                                                                                250-300
• During lactation
•          Basal                                                                                      150
•          0.5-1.1 L milk/day x 150-180 mgI/L                                  75-200
•                                                                                                                225-350
• Neonate and young infant
•         Term 15 mg/kg/day      )
•         Preterm 30 mg/kg/day) x 3-6 kgs                                           90
• Delange: Int J Endocrinol Metab 2: 1, 2004                         
•